Obesity Linked to Ovarian Cancer
Title: Obesity Linked to Ovarian Cancer Category: Health News Created: 1/6/2009 2:00:00 AM Last Editorial Review: 1/6/2009 Tue, 6 Jan 2009 00:00:00 PDT
Health Tip: Bones, Muscles and Aging
Title: Health Tip: Bones, Muscles and Aging Category: Health News Created: 1/3/2009 2:00:00 AM Last Editorial Review: 1/5/2009 Mon, 5 Jan 2009 00:00:00 PDT
Health Highlights: Jan. 1, 2009
Title: Health Highlights: Jan. 1, 2009 Category: Health News Created: 1/2/2009 2:00:00 AM Last Editorial Review: 1/2/2009 Fri, 2 Jan 2009 00:00:00 PDT
Genes Predict Chances of Breast Cancer's Spread
Title: Genes Predict Chances of Breast Cancer's Spread Category: Health News Created: 1/2/2009 2:00:00 AM Last Editorial Review: 1/2/2009 Fri, 2 Jan 2009 00:00:00 PDT
Study Links Osteoporosis Drugs to Jaw Trouble
Title: Study Links Osteoporosis Drugs to Jaw Trouble Category: Health News Created: 1/2/2009 2:00:00 AM Last Editorial Review: 1/2/2009 Fri, 2 Jan 2009 00:00:00 PDT
ScienceDaily: Cancer News Tue, 06 Jan 2009 18:05:01 EST
Obesity Linked To Elevated Risk Of Ovarian Cancer
A new epidemiological study has found that among women who have never used menopausal hormone therapy, obese women are at an increased risk of developing ovarian cancer compared with women of normal weight. Tue, 06 Jan 2009 14:00:00 EST
Protein's Essential Role In Repairing Damaged Cells Revealed
Researchers have discovered that a key protein in cells plays a critical role in not one, but two processes affecting the development of cancer. Tue, 06 Jan 2009 00:00:00 EST
Dormant Cancer Cells Rely On Cellular Self-cannibalization To Survive
A tumor-suppressing gene is a key to understanding, and perhaps killing, dormant ovarian cancer cells that persist after initial treatment only to reawaken later, researchers report. They found that expression of ARHI turns on autophagy, or self-eating, in ovarian cancer cells, which promotes their survival in a dormant state. Mon, 05 Jan 2009 20:00:00 EST
Newly Identified Gene Powerful Predictor Of Colon Cancer Metastasis
Scientists have identified a gene which enables them to predict for the first time with high probability if colon cancer is going to metastasize. They were able to demonstrate that the gene MACC1 not only promotes tumor growth but also the development of metastasis. When MACC1 gene activity is low, the life expectancy of patients with colon cancer is longer in comparison to patients with high MACC1 levels. Mon, 05 Jan 2009 20:00:00 EST
In Lung Cancer, Silencing One Crucial Gene Disrupts Normal Functioning Of Genome
While examining patterns of DNA modification in lung cancer, scientists have discovered what they say is a surprising new mechanism. They say that "silencing" of a single gene in lung cancer led to a general impairment in genome-wide changes in cells, contributing to cancer development and progression. Mon, 05 Jan 2009 14:00:00 EST
Differentiating Between Healthy Cells And Cancer Cells
One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process. But a new study by McMaster University researchers has provided insight into how scientists might develop therapies and drugs that more carefully target cancer, while sparing normal healthy cells Mick Bhatia, scientific director of the McMaster Stem Cell and Cancer Research Institute in the Michael G. Tue, 06 Jan 2009 07:00:00 PST
Discovery Of 'Relocation' Plan Of Metastatic Cancer Cells
Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. Tripping nimbly from one abode to another, these migrating cancer cells often prove far more deadly than the original tumor. Although little has been known about how these rogue cells choose where to put down roots, researchers at the Stanford University School of Medicine have now learned just how nefarious they are. Tue, 06 Jan 2009 06:00:00 PST
"On Switch" For Cell Death Signaling Mechanism Discovered By Burnham Researchers
Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell death). The research, performed by Stefan Riedl, Ph.D., and colleagues, published online on Dec. Tue, 06 Jan 2009 06:00:00 PST
Improved Understanding Of Complex Mechanisms That Regulate DNA Damage Control And Replication In The Cell Cycle
Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication and reinitiating replication following DNA repair. Since Ddk is often deregulated in human cancers, this new understanding of its role in DNA damage control could help shape new cancer therapies. The research was published in the Tue, 06 Jan 2009 06:00:00 PST
Treadmill Desks More Effective In Cancer Prevention For Women Than Vitamin C, E And Beta Carotene Supplementation
Yet another study published online by the Journal of the National Cancer Institute confirmed that vitamin supplementation provided no statistically significant value in cancer prevention among women. This study comes on the heels of numerous studies which all draw the same conclusion: vitamin supplementation among a normally well nourished population has no positive effect on cancer prevention. Tue, 06 Jan 2009 05:00:00 PST
New Insight Into Aggressive Childhood Cancer
A new study reveals critical molecular mechanisms associated with the development and progression of human neuroblastoma, the most common cancer in young children. The research, published by Cell Press in the January 6th issue of the journal Cancer Cell, may lead to development of future strategies for treatment of this aggressive and unpredictable cancer. Tue, 06 Jan 2009 04:00:00 PST
Inflammatory Breast Cancer: A Complex Disease
This article reviews the following: "Molecular Determinants of the Inflammatory Breast Cancer Phenotype". Tue, 06 Jan 2009 02:00:00 PST
21st Century Challenge Of Ovarian Cancer In The Elderly, A Personal Perspective - Cancernetwork.com
The incidence of ovarian cancer is highest in women over 70 years old, and the disease is the leading cause of death from gynecologic malignancies in the United States and Europe. Nevertheless, improving the quality of medical care for elderly women with ovarian cancer continues to be a challenge. Tue, 06 Jan 2009 02:00:00 PST
New Hope For Cancer Comes Straight From The Heart
Digitalis-based drugs like digoxin have been used for centuries to treat patients with irregular heart rhythms and heart failure and are still in use today. In the Dec. 16 issue of the Proceedings of the National Academy of Sciences, researchers at the Johns Hopkins University School of Medicine now report that this same class of drugs may hold new promise as a treatment for cancer. This finding emerged through a search for existing drugs that might slow or stop cancer progression. Tue, 06 Jan 2009 01:00:00 PST
2nd Eastern Mediterranean Meeting Of The European Association Of Urology Expected To Highlight Cystectomy
Because the 1st Eastern Mediterranean Meeting (EMM), which was held in Antalya (TR) in 2007, was a great success the 'second edition' will be organised on 23 and 24 January 2009 in the Pyramisa hotel in Cairo (EG). Approximately 250 participants from the eastern Mediterranean area are expected to participate. Tue, 06 Jan 2009 01:00:00 PST
Scientists at my alma mater, the University of Arkansas for Medical Sciences, plan to begin clinical trials this spring on a vaccine to prevent the recurrence of breast cancer.
Racial disparities in end of life cancer care may be caused by a preference for continuing aggressive treatment – a decision that blocks enrollment in hospice care – according to a study by Jessica Fishman, PhD and David J. Casarett, MD, MA, of the University of Pennsylvania School of Medicine and Veterans Affairs Center for Health Equity Research and Promotion, and colleagues.
Today I was thinking about what cancer drugs might be good to watch out for this year, such as abiraterone from Cougar Biotech currently being tested in prostate and breast cancers and Affinitor from Novartis, which is expecting FDA approval this year in renal cancer. A quick Google search turned up
New research in mice and five independent collections of human breast tumors has enabled National Cancer Institute (NCI) scientists to confirm that genes for factors contributing to susceptibility for breast cancer metastasis can be inherited. The new findings support earlier results from the same laboratory and appear in Cancer Research.
The FDA has reported a link between osteoporosis drugs and cancer of the esophagus. The findings are published January 1 in the New England Journal of Medicine.
Close encounters with 3-D cell growth
MIT engineers have built a device that gives them an unprecedented view of three-dimensional cell growth and migration, including the formation of blood vessels and the spread of tumor cells. Tue, 16 Dec 2008 00:00:00 EST
Nanotubes sniff out cancer agents in living cells
MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells. The sensors can detect chemotherapy drugs as well as environmental toxins and free radicals that damage DNA. Sun, 14 Dec 2008 00:00:00 EST
Reversing the conventional DNA wisdom
In work that represents a fundamental shift in scientists' understanding of DNA transcription, MIT researchers have found evidence that two DNA copying machines frequently start from the same site and move in different directions. Thu, 4 Dec 2008 00:00:00 EST
Going under the (robotic) knife
On Nov. 24, MIT students will show off their robotic engineering skills. They have been building robotic arms and writing software that will allow them to remotely make an incision in a silicone "organ" and remove a jelly bean masquerading as a tumor. Mon, 17 Nov 2008 00:00:00 EST
Untangling DNA regulation
MIT biologists have discovered that the organization of DNA's packing material plays a critical role in directing stem cells to become different types of adult cells. The work could also shed light on the possible role of DNA packaging in cancer development. Thu, 6 Nov 2008 00:00:00 EST
